Genomic and Proteomic Profiles Reveal the Association of Gelsolin to TP53 Status and Bladder Cancer Progression

Bladder cancer transformation and immortalization require the inactivation of key regulatory genes, including TP53. Genotyping of a large cohort of bladder cancer patients (n = 256) using the TP53 GeneChip showed mutations in 103 cases (40.2%), the majority of them mapping to the DNA-binding core do...

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Detalhes bibliográficos
Main Authors: Sanchez-Carbayo, Marta, Socci, Nicholas D., Richstone, Lee, Corton, Marta, Behrendt, Nille, Wulkfuhle, Julia, Bochner, Bernard, Petricoin, Emmanuel, Cordon-Cardo, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043525/
https://ncbi.nlm.nih.gov/pubmed/17982131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070338
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