Stromal Fibroblasts in Colorectal Liver Metastases Originate From Resident Fibroblasts and Generate an Inflammatory Microenvironment

Cancer-associated stromal fibroblasts (CAFs) are the main cellular constituents of reactive stroma in primary and metastatic cancer. We analyzed phenotypical characteristics of CAFs from human colorectal liver metastases (CLMs) and their role in inflammation and cancer progression. CAFs displayed a...

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Bibliographic Details
Main Authors: Mueller, Lars, Goumas, Freya A., Affeldt, Marianne, Sandtner, Susanne, Gehling, Ursula M., Brilloff, Silke, Walter, Jessica, Karnatz, Nadia, Lamszus, Katrin, Rogiers, Xavier, Broering, Dieter C.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043521/
https://ncbi.nlm.nih.gov/pubmed/17916596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060661
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