Stromal Fibroblasts in Colorectal Liver Metastases Originate From Resident Fibroblasts and Generate an Inflammatory Microenvironment

Cancer-associated stromal fibroblasts (CAFs) are the main cellular constituents of reactive stroma in primary and metastatic cancer. We analyzed phenotypical characteristics of CAFs from human colorectal liver metastases (CLMs) and their role in inflammation and cancer progression. CAFs displayed a...

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Detalhes bibliográficos
Main Authors: Mueller, Lars, Goumas, Freya A., Affeldt, Marianne, Sandtner, Susanne, Gehling, Ursula M., Brilloff, Silke, Walter, Jessica, Karnatz, Nadia, Lamszus, Katrin, Rogiers, Xavier, Broering, Dieter C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043521/
https://ncbi.nlm.nih.gov/pubmed/17916596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060661
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