Human Pancreatic Secretory Trypsin Inhibitor Stabilizes Intestinal Mucosa against Noxious Agents

Pancreatic secretory trypsin inhibitor (PSTI) is a serine protease inhibitor, expressed in gut mucosa, whose function is unclear. We, therefore, examined the effects of PSTI on gut stability and repair. Transgenic mice overexpressing human PSTI within the jejunum (FABPi(−1178 to +28) hPSTI construct...

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Autori principali: Marchbank, Tania, Mahmood, Asif, Fitzgerald, Anthony J., Domin, Jan, Butler, Matt, Goodlad, Robert A., Elia, George, Cox, Helen M., van Heel, David A., Ghosh, Subrata, Playford, Raymond J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2007
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043508/
https://ncbi.nlm.nih.gov/pubmed/17982125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070192
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