Human Pancreatic Secretory Trypsin Inhibitor Stabilizes Intestinal Mucosa against Noxious Agents

Pancreatic secretory trypsin inhibitor (PSTI) is a serine protease inhibitor, expressed in gut mucosa, whose function is unclear. We, therefore, examined the effects of PSTI on gut stability and repair. Transgenic mice overexpressing human PSTI within the jejunum (FABPi(−1178 to +28) hPSTI construct...

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Detalhes bibliográficos
Main Authors: Marchbank, Tania, Mahmood, Asif, Fitzgerald, Anthony J., Domin, Jan, Butler, Matt, Goodlad, Robert A., Elia, George, Cox, Helen M., van Heel, David A., Ghosh, Subrata, Playford, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043508/
https://ncbi.nlm.nih.gov/pubmed/17982125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070192
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