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Characterization of Metacaspases with Trypsin-Like Activity and Their Putative Role in Programmed Cell Death in the Protozoan Parasite Leishmania

In this report, we have characterized two metacaspases of Leishmania donovani, L. donovani metacaspase-1 (LdMC1) and LdMC2. These two proteins show 98% homology with each other, and both contain a characteristic C-terminal proline-rich domain. Both genes are transcribed in promastigotes and axenic a...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Nancy, Gannavaram, Sreenivas, Selvapandiyan, Angamuthu, Debrabant, Alain
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043384/
https://ncbi.nlm.nih.gov/pubmed/17715367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00123-07
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