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Distinct evolutionary mechanisms for genomic imbalances in high-risk and low-risk neuroblastomas

BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumour of childhood. Several genomic imbalances correlate to prognosis in NB, with structural rearrangements, including gene amplification, in a near-diploid setting typically signifying high-risk tumours and numerical changes in a...

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Main Authors: Gisselsson, David, Lundberg, Gisela, Øra, Ingrid, Höglund, Mattias
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042979/
https://ncbi.nlm.nih.gov/pubmed/17897457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-6-15
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