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Unique helical conformation of the fourth cytoplasmic loop of the CB(1) cannabinoid receptor in a negatively charged environment(†)
The proximal portion of the C-terminus of the CB(1) cannabinoid receptor is a primary determinant for G-protein activation. A seventeen residue proximal C-terminal peptide (rodent CB(1)401–417), the intracellular loop 4 (IL4) peptide, mimicked the receptor’s G-protein activation domain. Because of t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042966/ https://ncbi.nlm.nih.gov/pubmed/17524664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2007.04.004 |
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