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Preservation of mitochondrial function may contribute to cardioprotective effects of Na(+)/Ca(2+) exchanger inhibitors in ischaemic/reperfused rat hearts

BACKGROUND AND PURPOSE: Na(+)/Ca(2+) exchanger (NCX) inhibitors are known to attenuate myocardial reperfusion injury. However, the exact mechanisms for the cardioprotection remain unclear. The present study was undertaken to examine the mechanism underlying the cardioprotection by NCX inhibitors aga...

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Detalhes bibliográficos
Main Authors: Motegi, K, Tanonaka, K, Takenaga, Y, Takagi, N, Takeo, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042925/
https://ncbi.nlm.nih.gov/pubmed/17549042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707321
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