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Preservation of mitochondrial function may contribute to cardioprotective effects of Na(+)/Ca(2+) exchanger inhibitors in ischaemic/reperfused rat hearts

BACKGROUND AND PURPOSE: Na(+)/Ca(2+) exchanger (NCX) inhibitors are known to attenuate myocardial reperfusion injury. However, the exact mechanisms for the cardioprotection remain unclear. The present study was undertaken to examine the mechanism underlying the cardioprotection by NCX inhibitors aga...

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Bibliografski detalji
Glavni autori: Motegi, K, Tanonaka, K, Takenaga, Y, Takagi, N, Takeo, S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042925/
https://ncbi.nlm.nih.gov/pubmed/17549042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707321
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