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Double pharmacological challenge on repolarization opens new avenues for drug safety research
The pharmaceutical industry is testing new potential drugs for their propensity to prolong human cardiac repolarization, and regards this as a sign of proarrhythmic risk. Many studies have dethroned the common perception that prolonged repolarization is a reliable surrogate marker for torsades de po...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042920/ https://ncbi.nlm.nih.gov/pubmed/17549050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707299 |
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