Dose- and time-dependency of the dilator effects of the endothelin antagonist, BQ-123, in the human forearm

Aims Endothelin-1 is a potent endogenous vasoconstrictor that acts on the endothelin A (ET(A) ) receptor. The dose-response and time-course of the dilator effect of the ET(A) receptor antagonist, BQ-123, was investigated in the forearm of healthy volunteers. Methods Forearm blood flow was measured u...

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Bibliographic Details
Main Authors: Berrazueta, José R., Bhagat, Kiran, Vallance, Patrick, MacAllister, Raymond J.
Format: Artigo
Language:Inglês
Published: 1997
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042881/
https://ncbi.nlm.nih.gov/pubmed/9431833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.t01-1-00631.x
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