No effect of short-term omeprazole intake on acenocoumarol pharmacokinetics and pharmacodynamics

Aims To investigate the effect of omeprazole on the pharmacokinetics of R- and S-acenocoumarol and on their combined anticoagulant activity. Methods Eight healthy male subjects completed a double-blind, randomized, placebo-controlled, two-way cross-over study. Subjects were given either omeprazole 4...

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Autors principals: de Hoon, J. N. J. M., Thijssen, H. H. W., Beysens, A. J. M. M., Van Bortel, L. M. A. B.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042852/
https://ncbi.nlm.nih.gov/pubmed/9354316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00600.x
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