Pharmacokinetics of the S(+) and R(−) enantiomers of vigabatrin during chronic dosing in a patient with renal failure

Aims To study the pharmacokinetics of vigabatrin in a patient affected with tuberous sclerosis who developed major agitation and aggression, while receiving vigabatrin orally (1.5 g every 12 h) and in whom impaired renal function was diagnosed. Methods The patient received vigabatrin (0.5 g day(−1) ...

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Bibliografiske detaljer
Main Authors: Jacqz-Aigrain, Evelyne, Guillonneau, Marianne, Rey, Elisabeth, Macher, Marie-Alice, Montes, Christine, Chiron, Catherine, Loirat, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042814/
https://ncbi.nlm.nih.gov/pubmed/9278207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00636.x
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