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Population analysis of the non linear red blood cell partitioning and the concentration-effect relationship of draflazine following various infusion rates
Aims To investigate the impact of the specific red blood cell binding on the pharmacokinetics and pharmacodynamics of the nucleoside transport inhibitor draflazine after i.v. administration at various infusion rates. It was also aimed to relate the red blood cell (RBC) occupancy of draflazine to the...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wiley-Blackwell
1997
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042791/ https://ncbi.nlm.nih.gov/pubmed/9205820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00593.x |
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