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1-Methylxanthine derived from caffeine as a pharmacodynamic probe of oxypurinol effect

Aims In the present study we have investigated the use of caffeine, administered in the form of instant coffee, as a prodrug for 1MX to validate the use of the 1MU:1MX ratio following caffeine administration as a pharmacodynamic measure of oxypurinol effect on xanthine oxidase. Methods Five healthy...

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Detalhes bibliográficos
Main Authors: Birkett, D. J., Miners, J. O., Valente, L., Lillywhite, K. J., Day, R. O.
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042732/
https://ncbi.nlm.nih.gov/pubmed/9131954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.53711.x
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