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Limited value of the urinary phenytoin metabolic ratio for the assessment of cytochrome P4502C9 activity in vivo

Relationships between the ratio of p-hydroxyphenytoin (p-HPPH), the major metabolite of phenytoin, to unchanged phenytoin excreted in urine (the urinary metabolic ratio or MR) were compared with a number of indices of the metabolic clearances of phenytoin and tolbutamide published previously for sev...

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Bibliografske podrobnosti
Main Authors: TASSANEEYAKUL, WICHITTRA, BIRKETT, DONALD J., PASS, MICHAEL C., MINERS, JOHN O.
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042709/
https://ncbi.nlm.nih.gov/pubmed/8971435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.00496.x
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