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Dentate gyrus-specific manipulation of β-Ca(2+)/calmodulin-dependent kinase II disrupts memory consolidation

Although the functions of α-Ca(2+)/calmodulin-dependent kinase II (CaMKII) have been studied extensively, the role of βCaMKII, a coconstituent of the CaMKII holoenzyme in synaptic plasticity, learning, and memory has not been examined in vivo. Here we produce a transgenic mouse line in which the ind...

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Detalhes bibliográficos
Main Authors: Cho, Min H., Cao, Xiaohua, Wang, Deheng, Tsien, Joe Z.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042204/
https://ncbi.nlm.nih.gov/pubmed/17913888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703344104
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