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Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints
In this study, we address the function of Transforming Growth Factor beta (TGF-β) and its Type II receptor (Tgfbr2) in limb development in vivo. Mouse embryos were generated in which the Tgfbr2 gene was deleted in early limb mesenchyme using Prx1Cre-mediated LoxP recombination. A high level of Tgfbr...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042108/ https://ncbi.nlm.nih.gov/pubmed/17822689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.07.040 |
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