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A peptide signal for adapter protein mediated degradation by the AAA(+) protease ClpCP
ComS is an anti-adapter protein that binds to MecA, displacing the competence transcription factor ComK. This protects ComK from degradation by the ClpCP protease and turns on the switch leading to bistable gene expression. Here we identify the motifs on ComK and ComS that mediate binding to MecA, a...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2041856/ https://ncbi.nlm.nih.gov/pubmed/17560370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.05.011 |
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