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Stereoselective fungal metabolism of 7,12-dimethylbenz[a]anthracene: identification and enantiomeric resolution of a K-region dihydrodiol.

Syncephalastrum racemosum UT-70 and Cunninghamella elegans ATCC 36112 metabolized 7,12-dimethylbenz[a]anthracene (7,12-DMBA) to hydroxymethyl metabolites as well as 7-hydroxymethyl-12-methylbenz[a]anthracene trans-3,4-, -5,6-, -8,9-, and -10,11-dihydrodiols. The 7,12-DMBA metabolites were isolated b...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Principais autores: McMillan, D C, Fu, P P, Cerniglia, C E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3122656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.53.10.2560-2566.1987
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