Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats.

Virgin and breeder, male and female, Sprague-Dawley rats were unilaterally nephrectomized and given 1% saline drinking water. Animals were injected i.p., twice daily, with a 10 mg/100 g body wt dose of the 11-beta hydroxylation inhibitor, Metyrapone. After 7 weeks of treatment, both the previously n...

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Main Authors: Wexler, B. C., Greenberg, B. P.
Format: Artigo
Sprog:Inglês
Udgivet: 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041307/
https://ncbi.nlm.nih.gov/pubmed/638031
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