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Physical interaction between retinoic acid receptor and the oncoprotein Myb inhibits retinoic acid-dependent transactivation

The c-myb protooncogene is predominantly expressed in hematopoietic cells and plays a vital role in hematopoiesis. Retinoic acid (RA) is able to induce differentiation of several hematopoietic cells. This differentiation is linked to decreased c-myb expression, suggesting that retinoid receptors (RA...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Pfitzner, Edith, Kirfel, Jutta, Becker, Peter, Rolke, Andreas, Schüle, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20413/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9576918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.10.5539
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