Hepatic necrosis and glutathione depletion in captopril-treated mice.

Captopril (CP) is an angiotensin-converting enzyme inhibitor whose metabolism involves endogenous thiols which may be depleted at high doses of CP. Following intraperitoneal administration of CP (50-300 mg/kg), dose-dependent depletion of hepatic glutathione, increased serum transaminase (SGPT) leve...

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Detalles Bibliográficos
Main Authors: Helliwell, T. R., Yeung, J. H., Park, B. K.
Formato: Artigo
Idioma:Inglês
Publicado: 1985
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041016/
https://ncbi.nlm.nih.gov/pubmed/3882119
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