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Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands

Transformation of both prokaryotes and eukaryotes with single-stranded oligonucleotides can transfer sequence information from the oligonucleotide to the chromosome. We have studied this process using oligonucleotides that correct a −1 frameshift mutation in the LYS2 gene of Saccharomyces cerevisiae...

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Detalhes bibliográficos
Main Authors: Kow, Yoke W., Bao, Gaobin, Reeves, Jason W., Jinks-Robertson, Sue, Crouse, Gray F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040902/
https://ncbi.nlm.nih.gov/pubmed/17592146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704695104
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