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Defining functional distance using manifold embeddings of gene ontology annotations
Although rigorous measures of similarity for sequence and structure are now well established, the problem of defining functional relationships has been particularly daunting. Here, we present several manifold embedding techniques to compute distances between Gene Ontology (GO) functional annotations...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040899/ https://ncbi.nlm.nih.gov/pubmed/17595300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702965104 |
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