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Crystal structure of the channel-forming polypeptide antiamoebin in a membrane-mimetic environment

Crystals of an ion-channel-forming peptaibol peptide in a partial membrane environment have been obtained by cocrystallizing antiamoebin with n-octanol. The antiamoebin molecule has a bent helical conformation very similar to that established for Leu-zervamicin, despite a significantly different seq...

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Autors principals: Karle, Isabella L., Perozzo, Mary Ann, Mishra, Vinod K., Balaram, Padmanabhan
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20406/
https://ncbi.nlm.nih.gov/pubmed/9576911
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