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The pathology of halothane hepatotoxicity in a guinea-pig model: a comparison with human halothane hepatitis.

The pathology of halothane hepatotoxicity is described in detail in a guinea-pig model. Twenty-two of 40 guinea-pigs developed liver damage after exposure to 1% halothane in 21% O2 for 4 h. The other 18 animals showed no evidence of hepatic injury. Two distinct patterns of damage were identified: mi...

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Detalhes bibliográficos
Main Authors: Lunam, C. A., Hall, P. M., Cousins, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040590/
https://ncbi.nlm.nih.gov/pubmed/2818932
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