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Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation

We describe here a new component of the phosphatidylinositol 3-kinase/Akt signaling pathway that directly impacts mitochondria. Akt (protein kinase B) was shown for the first time to be localized in mitochondria, where it was found to reside in the matrix and the inner and outer membranes, and the l...

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Detalhes bibliográficos
Main Authors: Bijur, Gautam N., Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040497/
https://ncbi.nlm.nih.gov/pubmed/14713298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1471-4159.2003.02113.x
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