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Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis

A recently discovered phosphatidylinositol monophosphate, phosphatidylinositol 5-phosphate (PtdIns-5-P), plays an important role in nuclear signaling by influencing p53-dependent apoptosis. It interacts with a plant homeodomain finger of inhibitor of growth protein-2, causing an increase in the acet...

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Bibliographic Details
Main Authors: Zou, Jun, Marjanovic, Jasna, Kisseleva, Marina V., Wilson, Monita, Majerus, Philip W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040409/
https://ncbi.nlm.nih.gov/pubmed/17940011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708189104
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