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Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study

Endothelial dysfunction contributes to the development of coronary heart disease (CHD). Soluble epoxide hydrolase metabolizes epoxyeicosatrienoic acids in the vasculature and regulates endothelial function. We sought to determine whether genetic variation in soluble epoxide hydrolase (EPHX2) was ass...

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Detalhes bibliográficos
Main Authors: Lee, Craig R., North, Kari E., Bray, Molly S., Fornage, Myriam, Seubert, John M., Newman, John W., Hammock, Bruce D., Couper, David J., Heiss, Gerardo, Zeldin, Darryl C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040335/
https://ncbi.nlm.nih.gov/pubmed/16595607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddl085
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