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Adenylate Kinase 5 Autoimmunity in Treatment Refractory Limbic Encephalitis

We report two men with limbic encephalitis (LE) refractory to corticosteroids, IVIg and plasma exchange. Both patients had serum/CSF antibodies that reacted with the cytoplasm of neurons. Probing of a hippocampal cDNA library resulted in the isolation of adenylate kinase 5 (AK5). Patients' anti...

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Bibliographic Details
Main Authors: Tüzün, Erdem, Rossi, Jeffrey E., Karner, Steve F., Centurion, Alejandro F., Dalmau, Josep
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040128/
https://ncbi.nlm.nih.gov/pubmed/17462746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.03.015
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