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Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates

In all biological systems, protein amount is a function of the rate of production and clearance. The speed of a response to a disturbance in protein homeostasis is determined by turnover rate. Quantifying alterations in protein synthesis and clearance rates is vital to understanding disease pathogen...

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Detalhes bibliográficos
Main Authors: Bateman, Randall J., Munsell, Ling Y., Chen, Xianghong, Holtzman, David M., Yarasheski, Kevin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040126/
https://ncbi.nlm.nih.gov/pubmed/17383190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2007.02.009
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