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Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates
In all biological systems, protein amount is a function of the rate of production and clearance. The speed of a response to a disturbance in protein homeostasis is determined by turnover rate. Quantifying alterations in protein synthesis and clearance rates is vital to understanding disease pathogen...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040126/ https://ncbi.nlm.nih.gov/pubmed/17383190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2007.02.009 |
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