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Cell shape regulates global histone acetylation in human mammary epithelial cells

Extracellular matrix (ECM) regulates cell morphology and gene expression in vivo; these relationships are maintained in three-dimensional (3D) cultures of mammary epithelial cells. In the presence of laminin-rich ECM (lrECM), mammary epithelial cells round up and undergo global histone deacetylation...

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Autors principals: Le Beyec, Johanne, Xu, Ren, Lee, Sun-Young, Nelson, Celeste M., Rizki, Aylin, Alcaraz, Jordi, Bissell, Mina J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040058/
https://ncbi.nlm.nih.gov/pubmed/17524393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.04.022
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