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Improved anti-tumor activity and safety of interleukin-13 receptor targeted cytotoxin by systemic continuous administration in head and neck cancer xenograft model.

BACKGROUND: IL-13 receptor (IL-13R) targeted cytotoxin, IL13-PE38QQR, has been shown to have very potent anti-tumor activity to IL-13R-expressing head and neck tumor cells in vitro and in vivo. However, its effect is limited in aggressive tumors. To further improve the anti-tumor activity and safety...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kawakami, Koji, Husain, Syed R., Kawakami, Mariko, Puri, Raj K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040009/
https://ncbi.nlm.nih.gov/pubmed/12435859
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