Computer-based design of an HLA-haplotype and HIV-clade independent cytotoxic T-lymphocyte assay for monitoring HIV-specific immunity.

BACKGROUND: Human immunodeficiency virus (HIV)- specific CD8-positive cytotoxic T-lymphocytes (CTL) play a key role in controlling HIV infection. Monitoring CTL response could be clinically relevant during structured therapy interruption (STI), HIV exposure, and vaccine trials. However, HLA patients...

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Autors principals: Amicosante, Massimo, Gioia, Cristiana, Montesano, Carla, Casetti, Rita, Topino, Simone, D'Offizi, Gianpiero, Cappelli, Giulia, Ippolito, Giuseppe, Colizzi, Vittorio, Poccia, Fabrizio, Pucillo, Leopoldo P.
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039964/
https://ncbi.nlm.nih.gov/pubmed/12606814
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