Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.

BACKGROUND: Peroxynitrite is a cytotoxic oxidant formed from nitric oxide (NO) and superoxide. Tyrosine nitration, a footprint of peroxynitrite, has been demonstrated in the pancreatic islets as well as in the cardiovascular system of diabetic subjects. Delineation of the pathogenetic role of peroxy...

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Autori principali: Szabó, Csaba, Mabley, Jon G., Moeller, Suzanne M., Shimanovich, Roman, Pacher, Pál, Virag, László, Soriano, Francisco G., Van Duzer, John H., Williams, William, Salzman, Andrew L., Groves, John T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039946/
https://ncbi.nlm.nih.gov/pubmed/12477967
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