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Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.
BACKGROUND: Peroxynitrite is a cytotoxic oxidant formed from nitric oxide (NO) and superoxide. Tyrosine nitration, a footprint of peroxynitrite, has been demonstrated in the pancreatic islets as well as in the cardiovascular system of diabetic subjects. Delineation of the pathogenetic role of peroxy...
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Main Authors: | , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2002
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2039946/ https://ncbi.nlm.nih.gov/pubmed/12477967 |
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