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Identification and functional characterization of a human GalNAc [alpha]2,6-sialyltransferase with altered expression in breast cancer.

BACKGROUND: We sought to identify genes with altered expression during human breast cancer progression by applying mRNA comparisons of normal and tumor mammary cell lines with increasingly malignant phenotypes. The gene encoding a new sialyltransferase (STM) was found to be down-regulated in tumor c...

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Bibliographic Details
Main Authors: Sotiropoulou, Georgia, Kono, Mari, Anisowicz, Anthony, Stenman, Goran, Tsuji, Shuichi, Sager, Ruth
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039932/
https://ncbi.nlm.nih.gov/pubmed/11984005
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