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Stretch-Induced MAP Kinase Activation in Cardiac Myocytes: Differential Regulation through β(1)-Integrin and Focal Adhesion Kinase

Mitogen-activated protein (MAP) kinases have been implicated in hemodynamic load induced heart failure. Both angiotensin II (Ang II) and mechanical stretch activate MAP kinases in cardiac myocytes. In this study, we used a neonatal rat ventricular myocyte (NRVM) model to determine the role of focal-...

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Detalhes bibliográficos
Main Authors: Lal, H, Verma, SK, Smith, M, Guleria, RS, Lu, G, Foster, DM, Dostal, DE
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039913/
https://ncbi.nlm.nih.gov/pubmed/17583725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.05.012
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