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Averaging Tens to Hundreds of Icosahedral Particle Images to Resolve Protein Secondary Structure Elements using a Multi-Path Simulated Annealing Optimization Algorithm
Accurately determining a cryoEM particle’s alignment parameters is crucial to high resolution single particle 3-D reconstruction. We developed Multi-Path Simulated Annealing, a Monte Carlo type of optimization algorithm, for globally aligning the center and orientation of a particle simultaneously....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2039893/ https://ncbi.nlm.nih.gov/pubmed/17698370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2007.06.009 |
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