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CHARACTERIZATION OF THE IN VITRO METABOLISM OF SELECTIVE ANDROGEN RECEPTOR MODULATOR USING HUMAN, RAT, AND DOG LIVER ENZYME PREPARATIONS

Compound S4 [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] is a novel nonsteroidal selective androgen receptor modulator that demonstrates tissue-selective androgenic and anabolic effects. The purpose of this in vitro study was to identify the phas...

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Detalhes bibliográficos
Main Authors: Gao, Wenqing, Wu, Zengru, Bohl, Casey E., Yang, Jun, Miller, Duane D., Dalton, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039882/
https://ncbi.nlm.nih.gov/pubmed/16272404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.105.007112
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