Preoperative Chemoradiotherapy with Capecitabine and Oxaliplatin in Locally Advanced Rectal Cancer. A Phase I–II Multicenter Study of the Dutch Colorectal Cancer Group

BACKGROUND: We studied the maximum tolerated dose (MTD) and efficacy of oxaliplatin added to capecitabine and radiotherapy (Capox-RT) as neoadjuvant therapy for rectal cancer. METHODS: T3-4 rectal cancer patients received escalating doses of oxaliplatin (day 1 and 29) with a fixed dose of capecitabi...

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Autors principals: Hospers, Geke A., Punt, Cornelis J. A., Tesselaar, Margot E., Cats, Annemieke, Havenga, Klaas, Leer, Jan W. H., Marijnen, Corrie A., Jansen, Edwin P., Van Krieken, Han H. J. M., Wiggers, Theo, Van de Velde, Cornelis J. H., Mulder, Nanno H.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2007
Matèries:
Gastrointestinal Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039827/
https://ncbi.nlm.nih.gov/pubmed/17653805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-007-9396-6
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