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Properties, production, and applications of camelid single-domain antibody fragments

Camelids produce functional antibodies devoid of light chains of which the single N-terminal domain is fully capable of antigen binding. These single-domain antibody fragments (VHHs or Nanobodies®) have several advantages for biotechnological applications. They are well expressed in microorganisms a...

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Hlavní autoři: Harmsen, M. M., De Haard, H. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039825/
https://ncbi.nlm.nih.gov/pubmed/17704915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-007-1142-2
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