Histone Variant H2A.Z Marks the 5′ Ends of Both Active and Inactive Genes in Euchromatin

In S. cerevisiae, histone variant H2A.Z is deposited in euchromatin at the flanks of silent heterochromatin to prevent its ectopic spread. We show that H2A.Z nucleosomes are found at promoter regions of nearly all genes in euchromatin. They generally occur as two positioned nucleosomes that flank a...

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Autors principals: Raisner, Ryan M., Hartley, Paul D., Meneghini, Marc D., Bao, Marie Z., Liu, Chih Long, Schreiber, Stuart L., Rando, Oliver J., Madhani, Hiten D.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039754/
https://ncbi.nlm.nih.gov/pubmed/16239142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.10.002
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