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Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae

BACKGROUND: The nonsense-mediated mRNA decay (NMD) pathway promotes the rapid degradation of mRNAs containing premature termination codons (PTCs). In yeast Saccharomyces cerevisiae, the activity of the NMD pathway depends on the recognition of the PTC by the translational machinery. Translation term...

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Autores principales: Chabelskaya, Svetlana, Gryzina, Valentina, Moskalenko, Svetlana, Le Goff, Catherine, Zhouravleva, Galina
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039749/
https://ncbi.nlm.nih.gov/pubmed/17705828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-71
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