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Reductive inactivation of digitoxin by Eubacterium lentum cultures.

The obligate anaerobe Eubacterium lentum inactivated the cardiac glycoside digitoxin by reducing the double bond in the lactone ring. This conversion was quantitative when the substrate was incubated at a concentration of 10 micrograms/ml. The reduction reaction coincided with the growth phase of th...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Chandrasekaran, A, Robertson, L W, Reuning, R H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3579289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.53.4.901-904.1987
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