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Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation

Multiple endocrine neoplasia type 2 (MEN 2) is a dominantly inherited cancer syndrome that comprises three clinical subtypes: MEN type 2A (MEN-2A), MEN type 2B (MEN-2B), and familial medullary thyroid carcinoma (FMTC). Medullary thyroid carcinoma (MTC), a malignant tumor arising from calcitonin-secr...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Michiels, Francine-Marie, Chappuis, Sophie, Caillou, Bernard, Pasini, Andrea, Talbot, Monique, Monier, Roger, Lenoir, Gilbert M., Feunteun, Jean, Billaud, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.3330
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