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ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors

The proliferative action of ERα largely accounts for the carcinogenic activity of estrogens. By contrast, recent data show that ERβ displays tumor-suppressor properties, thus supporting the interest to identify compounds which could increase its activity. Here, we show that histone deacetylase inhib...

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Detalhes bibliográficos
Main Authors: Duong, Vanessa, Licznar, Anne, Margueron, Raphaël, Boulle, Nathalie, Busson, Muriel, Lacroix, Matthieu, Katzenellenbogen, Benita S., Cavaillès, Vincent, Lazennec, Gwendal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034758/
https://ncbi.nlm.nih.gov/pubmed/16158045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209102
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