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Evolution Can Favor Antagonistic Epistasis

The accumulation of deleterious mutations plays a major role in evolution, and key to this are the interactions between their fitness effects, known as epistasis. Whether mutations tend to interact synergistically (with multiple mutations being more deleterious than would be expected from their indi...

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Detalhes bibliográficos
Main Authors: Desai, Michael M., Weissman, Daniel, Feldman, Marcus W.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2007 by the Genetics Society of America 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034608/
https://ncbi.nlm.nih.gov/pubmed/17720923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.075812
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