Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain

BACKGROUND: The transmembrane presenilin (PSEN) proteins, PSEN1 and PSEN2, have been proposed to be the catalytic components of the γ-secretase protein complex, which is an intramembranous multimeric protease involved in development, cell regulatory processes, and neurodegeneration in Alzheimer'...

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Bibliografiske detaljer
Main Authors: Madsen, Lone B, Thomsen, Bo, Larsen, Knud, Bendixen, Christian, Holm, Ida E, Fredholm, Merete, Jørgensen, Arne L, Nielsen, Anders L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034586/
https://ncbi.nlm.nih.gov/pubmed/17854491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-72
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