Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions

Ancient DNA (aDNA) research has long depended on the power of PCR to amplify trace amounts of surviving genetic material from preserved specimens. While PCR permits specific loci to be targeted and amplified, in many ways it can be intrinsically unsuited to damaged and degraded aDNA templates. PCR a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brotherton, Paul, Endicott, Phillip, Sanchez, Juan J., Beaumont, Mark, Barnett, Ross, Austin, Jeremy, Cooper, Alan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2007
Gaiak:
Molecular Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034480/
https://ncbi.nlm.nih.gov/pubmed/17715147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm588
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